<scp>AI</scp> in chemical engineering: From promise to practice

Abstract Artificial intelligence (AI) in chemical engineering has moved from promise to practice: physics‐aware (gray‐box) models are gaining traction, reinforcement learning complements model predictive control (MPC), and generative AI powers documentation, digitization, and safety workflows. Near‐term value arises where AI augments, rather than replaces, process system engineering (PSE) practice (e.g., through soft sensing and surrogate models), while autonomous operations, fully automated hazard and operability (HAZOP) analysis, and large‐scale mechanistic discovery remain largely at the research stage. The decisive bottleneck is reliable deployment: AI models must be treated like any other engineered system, with validation, monitoring, and governance aligned with emerging frameworks such as the EU AI Act and NIST risk management framework (RMF). With incubator labs, open benchmarks, and retooled education pipelines, AI can become a safe, reliable, and sustainable co‐worker in the process industries within years.

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Institutions

Publication Details

Journal
AIChE Journal
Published
2026-03-16
DOI
https://doi.org/10.1002/aic.70358
Primary Topic
Process Optimization and Integration
Type
article
Field-Weighted Citation Impact
0.00
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article

AI in chemical engineering: From promise to practice

Thomas Bierweiler, Jia Wei Chew, Torsten Wik, Ronnie Andersson et al.
AIChE Journal
Process Optimization and Integration
article

AI in chemical engineering: From promise to practice

Thomas Bierweiler, Jia Wei Chew, Torsten Wik, Ronnie Andersson, Patrik Ryttestal
article en

Abstract

Abstract Artificial intelligence (AI) in chemical engineering has moved from promise to practice: physics‐aware (gray‐box) models are gaining traction, reinforcement learning complements model predictive control (MPC), and generative AI powers documentation, digitization, and safety workflows. Near‐term value arises where AI augments, rather than replaces, process system engineering (PSE) practice (e.g., through soft sensing and surrogate models), while autonomous operations, fully automated hazard and operability (HAZOP) analysis, and large‐scale mechanistic discovery remain largely at the research stage. The decisive bottleneck is reliable deployment: AI models must be treated like any other engineered system, with validation, monitoring, and governance aligned with emerging frameworks such as the EU AI Act and NIST risk management framework (RMF). With incubator labs, open benchmarks, and retooled education pipelines, AI can become a safe, reliable, and sustainable co‐worker in the process industries within years.

AIChE Journal
Siemens (Germany) (DE), Siemens (Sweden) (SE), Chalmers University of Technology (SE)
Industry, innovation and infrastructure
Openalex Percentile: Top 19%
Process Optimization and Integration
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