Prevalence of antisynthetase antibodies in a multicentre early rheumatoid arthritis cohort

We report that the presence of anti-ARS antibodies cannot be confirmed by IP in a multicentre cohort of untreated early RA patients. Anti-ARS autoantibodies should not routinely be evaluated in patients with early RA. Sensitivity and specificity issues with DIA and LIA for anti-ARS should be considered in the interpretation of anti-ARS testing.

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Publication Details

Journal
Acta Clinica Belgica
Published
2026-03-17
DOI
https://doi.org/10.1080/17843286.2026.2645165
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
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article

Prevalence of antisynthetase antibodies in a multicentre early rheumatoid arthritis cohort

Silke Willebrords, Minoru Satoh, Xavier Bossuyt, Jean‐Baptiste Vulsteke et al.
Acta Clinica Belgica
Inflammatory Myopathies and Dermatomyositis
article

Prevalence of antisynthetase antibodies in a multicentre early rheumatoid arthritis cohort

Silke Willebrords, Minoru Satoh, Xavier Bossuyt, Jean‐Baptiste Vulsteke, Bram Mariën, Ellen De Langhe, Johan Joly, Patrick Verschueren
article en

Abstract

We report that the presence of anti-ARS antibodies cannot be confirmed by IP in a multicentre cohort of untreated early RA patients. Anti-ARS autoantibodies should not routinely be evaluated in patients with early RA. Sensitivity and specificity issues with DIA and LIA for anti-ARS should be considered in the interpretation of anti-ARS testing.

Acta Clinica Belgica
University of Occupational and Environmental Health Japan (JP), ERN GUARD-Heart (NL), Kitakyushu City Hospital Organization (JP), KU Leuven (BE)
Zero hunger
Openalex Percentile: Top 21%
Inflammatory Myopathies and Dermatomyositis
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Prevalence of antisynthetase antibodies in a multicentre early rheumatoid arthritis cohort — Silke Willebrords, Minoru Satoh, et al. · Acta Clinica Belgica (2026) | TGRS Research Map | TGRS