Peroxidasin promotes malignant progression by enhancing glycolytic metabolism in glioblastoma through the regulation of LDHA
PXDN is identified as a potential diagnostic indicator for GBM, and PXDN promotes malignant progression in GBM by modulating LDHA. Anti-PXDN therapy may represent a viable new approach to combat GBM.
Authors
- Z. Jason Qian (ORCID: https://orcid.org/0000-0003-4150-1023)
- Chunlong Ding
- Yang Xu
- Quanquan Guo
Institutions
- Xuzhou Medical College (CN)
- Soochow University (CN)
- Zhongda Hospital Southeast University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Neurological Research
- Published
- 2026-03-17
- DOI
- https://doi.org/10.1080/01616412.2026.2647415
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00