Antibacterial Activity of Fresh and Autoclaved Platelet‐Rich Fibrin on <i>Pseudomonas aeruginosa</i> : An In Vitro Study

Both fresh and autoclaved PRF exhibited antibacterial activity against P. aeruginosa, with autoclaved PRF showing enhanced efficacy. Activity in methanol-extracted PRF indicates a potential role for heat-stable, non-protein components. These findings highlight thermally treated PRF as a sterilizable, bioactive biomaterial for infection-prone dental and surgical applications. Future studies should identify the specific antibacterial constituents and confirm their efficacy in vivo to support clinical translation.