Hypercholesterolemia and Lipid-Lowering Therapy in Children and Adolescents With Type 1 Diabetes: Do We Implement Current Guidelines?

We found a high prevalence of LDL hypercholesterolemia. The use of LLM was low, despite treatment indication, and treatment targets were mostly not achieved either due to underdosing or nonadherence to LLM. These findings confirm that dyslipidemia remains an underestimated cardiovascular risk factor in pediatric diabetology.

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Publication Details

Journal
Diabetes Care
Published
2026-03-17
DOI
https://doi.org/10.2337/dc25-2459
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
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article

Hypercholesterolemia and Lipid-Lowering Therapy in Children and Adolescents With Type 1 Diabetes: Do We Implement Current Guidelines?

Johanna Hammersen, Susanne Bechtold‐Dalla Pozza, Marie-Anne Burckhard, Reinhard Walter Holl et al.
Diabetes Care
Diabetes Management and Research
article

Hypercholesterolemia and Lipid-Lowering Therapy in Children and Adolescents With Type 1 Diabetes: Do We Implement Current Guidelines?

Johanna Hammersen, Susanne Bechtold‐Dalla Pozza, Marie-Anne Burckhard, Reinhard Walter Holl, Marianne Becker, Martin Holder, Jantje Weiskorn, Elke Müller-Roßberg, Clemens Kamrath
article en

Abstract

We found a high prevalence of LDL hypercholesterolemia. The use of LLM was low, despite treatment indication, and treatment targets were mostly not achieved either due to underdosing or nonadherence to LLM. These findings confirm that dyslipidemia remains an underestimated cardiovascular risk factor in pediatric diabetology.

Diabetes Care
Centre Hospitalier de Luxembourg (LU), University of Luxembourg (LU), University Medical Center Freiburg (DE), University Hospital of Basel (CH), Kinderkrankenhaus auf der Bult (DE), Universitätsklinikum Erlangen (DE), Olgahospital (DE), Klinikum Esslingen (DE), University Children’s Hospital Basel (CH), Deutsches Diabetes-Zentrum e.V. (DE), German Center for Diabetes Research (DE), Heinrich Heine University Düsseldorf (DE), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 21%
Diabetes Management and Research
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