Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population‐Based Cohort Study

Prenatal exposure to codeine and oxycodone do not have meaningful impacts on third-grade academic performance. In contrast, tramadol was associated with lower reading and numeracy scores, though whether this reflects a true effect or is attributable to unmeasured confounding remains unclear and warrants further investigation.

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Publication Details

Journal
BJOG An International Journal of Obstetrics & Gynaecology
Published
2026-03-15
DOI
https://doi.org/10.1111/1471-0528.70221
Primary Topic
Prenatal Substance Exposure Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population‐Based Cohort Study

Malcolm Bjørn Gillies, Antonia Shand, Helga Zoëga, Jonathan Brett et al.
BJOG An International Journal of Obstetrics & Gynaecology
Prenatal Substance Exposure Effects
article

Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population‐Based Cohort Study

Malcolm Bjørn Gillies, Antonia Shand, Helga Zoëga, Jonathan Brett, Claudia Bruno, Bianca Varney, Natasha Nassar, Alys Havard
article en

Abstract

Prenatal exposure to codeine and oxycodone do not have meaningful impacts on third-grade academic performance. In contrast, tramadol was associated with lower reading and numeracy scores, though whether this reflects a true effect or is attributable to unmeasured confounding remains unclear and warrants further investigation.

BJOG An International Journal of Obstetrics & Gynaecology
University of Technology Sydney (AU), The University of Sydney (AU), University of Iceland (IS), Royal Hospital for Women (AU), Children's Hospital at Westmead (AU), UNSW Sydney (AU), St Vincent's Health (AU), St Vincent's Clinic (AU), Mental Health Commission (AU)
Quality Education
Openalex Percentile: Top 19%
Prenatal Substance Exposure Effects
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