Jinshui Chenfei formula alleviates SiO2-induced pulmonary fibrosis by inhibiting macrophage M2 polarization via Grb2/STAT6 in rats
JCF downregulate STAT6 activation by regulating Grb2, thereby inhibit M2 polarization of macrophage and improve pulmonary fibrosis in silicotic rats.
Authors
- Xinguang Liu (ORCID: https://orcid.org/0000-0001-9033-9099)
- Runsu Hou
- Yange Tian
- Fan Yang
- Qin Zhang
- Xin Pan
- Jiansheng Li
- Peng Zhao
- Yan Du
Institutions
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1186/s13020-026-01339-7
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00