Antibacterial and Antioxidant Activities of <i>Cochlospermum</i><i> </i><i>planchonii</i> Hook Leaves and White Tips of <i>Agama </i>&

The aim of this study was to evaluate the antibacterial and antioxidant properties of three samples from aqueous extracts of <i>Cochlospermum</i><i> </i><i>planchonii</i> leaves and the white tips of <i>Agama </i><i>agama</i> feces. The phytochemical analyses were carried out by HPLC and spectrophotometric assays. The antioxidant activity was carried out by the DPPH method. As for antibacterial activity, it consisted of determining the inhibition percentage by solid disk diffusion. The Minimum Inhibitory Concentration (MIC) was then determined using the liquid dilution method in sterile test tubes. The phenolic profiles reveal the presence of twelve (12) phenolic compounds identified in the 3 samples E1, E2 and E3. All these phenolic compound showed a significant difference (p ≤ 0.05) when compared with each other. The best antioxidant activity was obtained with sample E2 (80.81 ± 1.36%) compared to vitamin C (59.7 ± 5.11%) used as a reference molecule. Sample E1 gave the best antibacterial activity against the pathogenic strains <i>Stahylococcus</i><i> </i><i>aureus</i><i> </i>(ATCC29213) and <i>Pseudomonas </i><i>aeruginosa</i><i> </i>(ATCC27853) with respective MICs of 250 mg/mL and 200 mg/mL. This better efficacy of sample E1 was confirmed by maximum inhibition zones of 14 mm against <i>Pseudomonas </i><i>aeruginosa</i> and 12 mm against <i>Staphylococcus </i><i>aureus</i> at the concentration of 500 mg/mL, corresponding to 15.55% and 13% inhibition respectively. This study showed a therapeutic potential of <i>Cochlospermum</i><i> </i><i>planchonii</i> and white tips of <i>Agama </i><i>agama</i> feces as a source of natural antimicrobial and antioxidant agents.