LVAD specific infection with Coxiella burnetii treated with heart transplantation and antibiotic suppression

We report a rare case of LVAD infection caused by Coxiella burnetii in a 43-year-old male. The infection was diagnosed after CT-guided abscess sampling, FISHseq analysis, and serology. Conservative therapy with doxycycline and hydroxychloroquine proved unsuccessful. After LVAD removal and heart transplantation, the patient has remained infection-free for three years under antibiotic suppression.

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Publication Details

Journal
European Journal of Clinical Microbiology & Infectious Diseases
Published
2026-03-16
DOI
https://doi.org/10.1007/s10096-026-05464-x
Primary Topic
Rabies epidemiology and control
Type
article
Field-Weighted Citation Impact
0.00

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article

LVAD specific infection with Coxiella burnetii treated with heart transplantation and antibiotic suppression

Jan Knierim, Judith Kikhney, Annette Moter, Andrej Trampuž et al.
European Journal of Clinical Microbiology & Infectious Diseases
Rabies epidemiology and control
article

LVAD specific infection with Coxiella burnetii treated with heart transplantation and antibiotic suppression

Jan Knierim, Judith Kikhney, Annette Moter, Andrej Trampuž, Lucka Kuntner, Felix Schoenrath, Nikolaos Cholevas, Evgenij Potapov
article en

Abstract

We report a rare case of LVAD infection caused by Coxiella burnetii in a 43-year-old male. The infection was diagnosed after CT-guided abscess sampling, FISHseq analysis, and serology. Conservative therapy with doxycycline and hydroxychloroquine proved unsuccessful. After LVAD removal and heart transplantation, the patient has remained infection-free for three years under antibiotic suppression.

European Journal of Clinical Microbiology & Infectious Diseases
Deutsches Herzzentrum München (DE), Berlin Heart (Germany) (DE), Charité - Universitätsmedizin Berlin (DE)
Bundesministerium für Bildung und Forschung
Good health and well-being
Openalex Percentile: Top 27%
Rabies epidemiology and control
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LVAD specific infection with Coxiella burnetii treated with heart transplantation and antibiotic suppression — Jan Knierim, Judith Kikhney, et al. · European Journal of Clinical Microbiology & Infectious Diseases (2026) | TGRS Research Map | TGRS