Monocyte Immunometabolic Axis Linking Type 2 Diabetes to Coronary Artery Disease Revealed by Multi-Omics Integration and Mendelian Randomization
Multi-omics integration and genetic analyses supported a monocyte-centered immunometabolic framework involving ADM, PGD, and ATG7 that was consistent with elevated CAD risk in T2D, and generated testable hypotheses.
Authors
- Feng Bai (ORCID: https://orcid.org/0009-0004-9685-1607)
- Min Zhai (ORCID: https://orcid.org/0000-0003-4930-4454)
- Rui Yan
- Min Liu
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
- Yuxian People's Hospital (CN)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1253/circj.cj-25-1057
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00