The prognostic value of systemic inflammatory response index (SIRI) in acute coronary syndrome patients treated with primary percutaneous coronary intervention: a meta-analysis and systematic review

Our meta-analysis demonstrates that an elevated SIRI is a useful predictor of all-cause mortality, MACE, new-onset AMI, and revascularization in patients with ACS undergoing PCI. As a simple and cost-effective index, SIRI shows significant potential for early risk stratification and may help guide clinical management in this patient population.

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Publication Details

Journal
Clinical Research in Cardiology
Published
2026-03-16
DOI
https://doi.org/10.1007/s00392-026-02889-4
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
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article

The prognostic value of systemic inflammatory response index (SIRI) in acute coronary syndrome patients treated with primary percutaneous coronary intervention: a meta-analysis and systematic review

Qianling Ye, Francesco Paneni, Christopher Dostal, Matthias Ernst et al.
Clinical Research in Cardiology
Inflammatory Biomarkers in Disease Prognosis
article

The prognostic value of systemic inflammatory response index (SIRI) in acute coronary syndrome patients treated with primary percutaneous coronary intervention: a meta-analysis and systematic review

Qianling Ye, Francesco Paneni, Christopher Dostal, Matthias Ernst, Gabor Tamas Szabó, Chenming Hu, P Pokreisz, B Podesser, Shunjie You, Si Li, Attila Kiss
article en

Abstract

Our meta-analysis demonstrates that an elevated SIRI is a useful predictor of all-cause mortality, MACE, new-onset AMI, and revascularization in patients with ACS undergoing PCI. As a simple and cost-effective index, SIRI shows significant potential for early risk stratification and may help guide clinical management in this patient population.

Clinical Research in Cardiology
University of Debrecen (HU), Affiliated Hospital of Southwest Medical University (CN), Meizhou City People's Hospital (CN), Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA (AT), University Hospital of Zurich (CH), Ludwig Boltzmann Institute for Age Research (AT), Ludwig Boltzmann Institute for Cancer Research (AT), Medical University of Vienna (AT)
Good health and well-being
Openalex Percentile: Top 20%
Inflammatory Biomarkers in Disease Prognosis
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