Effects of psychosocial interventions on cancer-related fatigue in patients with colorectal cancer: a systematic review and meta-analysis of randomised controlled trials

Psychosocial interventions, particularly psycho-behavioural approaches, appear effective in reducing CRF among patients with colorectal cancer; however, effects were consistent at medium-term and long-term follow-up, while short-term findings showed substantial heterogeneity. More rigorous, adequately powered trials are needed to strengthen and extend the current evidence base.