Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression
These results suggest that serum Aβ oligomers may predict a poor response to antidepressant treatment in middle-aged and late-life patients with depression. Our findings also lead us to speculate that elderly patients with a poor treatment response may share AD-related pathophysiological features or neural vulnerability.
Authors
- Seita Yasuda
- Hajime Baba (ORCID: https://orcid.org/0000-0001-9678-8776)
- Kentaro Shimizu (ORCID: https://orcid.org/0000-0002-3245-0052)
- Hitoshi Maeshima
- Tomoya Ichikawa
Institutions
- Juntendo University (JP)
- Juntendo University Shizuoka Hospital (JP)
- Juntendo University Urayasu Hospital (JP)
- Juntendo University Hospital (JP)
Publication Details
- Journal
- Neuropsychopharmacology Reports
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1002/npr2.70109
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00