Molecular epidemiology of the MTHFR C677T polymorphism and its association with type 2 diabetes mellitus at the University of Gondar Comprehensive Specialized Hospital

The study highlights integrating genetic profiling with targeted risk reduction. At-risk patients should adopt healthy lifestyles, undergo individualized T2DM screening, and avoid smoking and excess alcohol. Health facilities should strengthen screening and genetic counseling, with support from policymakers, researchers, NGOs, and community groups.

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Publication Details

Journal
Annals of Human Biology
Published
2026-03-16
DOI
https://doi.org/10.1080/03014460.2026.2632816
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Molecular epidemiology of the MTHFR C677T polymorphism and its association with type 2 diabetes mellitus at the University of Gondar Comprehensive Specialized Hospital

Nega Berhane, Muluken Dejen, Meera Indracanti, Genetu Kassahun Berie et al.
Annals of Human Biology
Folate and B Vitamins Research
article

Molecular epidemiology of the MTHFR C677T polymorphism and its association with type 2 diabetes mellitus at the University of Gondar Comprehensive Specialized Hospital

Nega Berhane, Muluken Dejen, Meera Indracanti, Genetu Kassahun Berie, Mequanente Dagnaw
article en

Abstract

The study highlights integrating genetic profiling with targeted risk reduction. At-risk patients should adopt healthy lifestyles, undergo individualized T2DM screening, and avoid smoking and excess alcohol. Health facilities should strengthen screening and genetic counseling, with support from policymakers, researchers, NGOs, and community groups.

Annals of Human BiologyVol. 53(1)
University of Health and Allied Sciences (GH), Czech Academy of Sciences, Institute of Biotechnology (CZ), University of Gondar (ET)
Good health and well-being
Openalex Percentile: Top 19%
Folate and B Vitamins Research
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