Childhood Mental Health and Body Mass Index as Mediators of Genetic Risk for Eating Disorders

Our findings suggest that genetic liability to eating disorders manifests early in life through distinct metabolic and psychosocial pathways, highlighting a window for sex-specific targeted prevention.

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Publication Details

Journal
medRxiv
Published
2026-03-16
DOI
https://doi.org/10.64898/2026.03.13.26347917
Primary Topic
Eating Disorders and Behaviors
Type
article
Field-Weighted Citation Impact
0.00

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article

Childhood Mental Health and Body Mass Index as Mediators of Genetic Risk for Eating Disorders

Adrianna P. Kępińska, Yen-Feng Lin, Gerome Breen, Chaoyu Liu et al.
medRxiv
Eating Disorders and Behaviors
article

Childhood Mental Health and Body Mass Index as Mediators of Genetic Risk for Eating Disorders

Adrianna P. Kępińska, Yen-Feng Lin, Gerome Breen, Chaoyu Liu, Jonathan RI Coleman, Jiayi Xu, Laura M Huckins, Cynthia Bulik
article en

Abstract

Our findings suggest that genetic liability to eating disorders manifests early in life through distinct metabolic and psychosocial pathways, highlighting a window for sex-specific targeted prevention.

medRxiv
University of North Carolina at Chapel Hill (US), National Health Research Institutes (TW), King's College London (GB), South London and Maudsley NHS Foundation Trust (GB), Karolinska Institutet (SE), Yale University (US), Center for Genomic Science (IT)
National Institute for Health and Care Research, National Health Research Institutes, National Science and Technology Council, National Institutes of Health, NIHR Maudsley Biomedical Research Centre, Medical Research Council, National Institute of Mental Health
Openalex Percentile: Top 24%
Eating Disorders and Behaviors
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Childhood Mental Health and Body Mass Index as Mediators of Genetic Risk for Eating Disorders — Adrianna P. Kępińska, Yen-Feng Lin, et al. · medRxiv (2026) | TGRS Research Map | TGRS