Case report: Malignant erythema in an ovarian cancer case: an uncommon paraneoplastic syndrome

Dermatomyositis is an autoimmune illness that affects the striated muscle and skin. It usually shows muscular and cutaneous manifestation. Age above 40 years and females are risk factors for malignant tumor in patients with dermatomyositis. In our case study, a woman with malignant erythema as her first symptom was reported. She was later diagnosed with ovarian cancer and underwent subtractive surgery, which caused the erythema to rapidly subside. Most similar DM cases suffered from muscular disorders including painless proximal symmetrical weakness as well as weakness of the pharyngeal muscle, often leading to aspiration pneumonia and dysphagia. Here, we reported this case with cutaneous symptoms in detailed clinical information including medicine use and clinical outcome. Cancer screening would be recommended in these intractable cases. On the other side, more researches are needed be focused on the immunity change of ovarian cancer.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-03-16
DOI
https://doi.org/10.3389/fonc.2026.1593511
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
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article

Case report: Malignant erythema in an ovarian cancer case: an uncommon paraneoplastic syndrome

Xingyu Wang, Lu Wang, Xiaolin Liu
Frontiers in Oncology
Inflammatory Myopathies and Dermatomyositis
article

Case report: Malignant erythema in an ovarian cancer case: an uncommon paraneoplastic syndrome

Xingyu Wang, Lu Wang, Xiaolin Liu
article en

Abstract

Dermatomyositis is an autoimmune illness that affects the striated muscle and skin. It usually shows muscular and cutaneous manifestation. Age above 40 years and females are risk factors for malignant tumor in patients with dermatomyositis. In our case study, a woman with malignant erythema as her first symptom was reported. She was later diagnosed with ovarian cancer and underwent subtractive surgery, which caused the erythema to rapidly subside. Most similar DM cases suffered from muscular disorders including painless proximal symmetrical weakness as well as weakness of the pharyngeal muscle, often leading to aspiration pneumonia and dysphagia. Here, we reported this case with cutaneous symptoms in detailed clinical information including medicine use and clinical outcome. Cancer screening would be recommended in these intractable cases. On the other side, more researches are needed be focused on the immunity change of ovarian cancer.

Frontiers in OncologyVol. 16
Zhejiang International Studies University (CN), Qilu Hospital of Shandong University (CN)
Good health and well-being
Openalex Percentile: Top 22%
Inflammatory Myopathies and Dermatomyositis
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Case report: Malignant erythema in an ovarian cancer case: an uncommon paraneoplastic syndrome — Xingyu Wang, Lu Wang, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS