Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
Most children with R/R solid tumors experience multiple events and therapy regimens without a break. Presence of a >30-day break did not negatively affect survival, implying that time between therapy regimens can safely be offered to select patients to promote quality of life and thoughtful decision-making, without compromising survival.
Authors
- Elizabeth Seashore
- Shondra Clay
- Jessica Casas (ORCID: https://orcid.org/0009-0001-8806-6156)
- Jennifer H. Foster (ORCID: https://orcid.org/0000-0002-2126-9768)
- Matthew T. McEvoy (ORCID: https://orcid.org/0000-0001-8767-0215)
- W. Susan Cheng
Institutions
- Northern Illinois University (US)
- Tulane University (US)
- UCSF Benioff Children's Hospital (US)
- Texas Children's Hospital (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1002/1545-5017.70199
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00