Adverse childhood experiences and sarcopenia: a prospective study embedded in the Canadian Longitudinal Study on Aging
ACEs are associated with modest declines in muscle mass and function, with depression emerging as a key pathway linking early adversity to later-life sarcopenia. These findings highlight the need to integrate psychosocial history and mental health into risk stratification and preventive strategies for functional decline.
Authors
- Hans W. Jeuring (ORCID: https://orcid.org/0000-0002-0131-0735)
- Emiel O. Hoogendijk (ORCID: https://orcid.org/0000-0001-9660-5108)
- Kitty J.E. Kokkeler (ORCID: https://orcid.org/0000-0001-5374-4685)
- Menelaos Dimitriadis (ORCID: https://orcid.org/0000-0001-5150-5074)
- Iván Aprahamian (ORCID: https://orcid.org/0000-0003-3806-7895)
- Radboud M. Marijnissen (ORCID: https://orcid.org/0000-0003-0259-7480)
- R C Oude Voshaar
Institutions
- University Medical Center Groningen (NL)
- Amsterdam Neuroscience (NL)
- Faculdade de Medicina de Jundiaí (BR)
- Pro Persona (NL)
Publication Details
- Journal
- Age and Ageing
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1093/ageing/afag050
- Primary Topic
- Child Abuse and Trauma
- Type
- article
- Field-Weighted Citation Impact
- 0.00