Cardiac Biomarkers Response Under Angiotensin Receptor–Neprilysin Inhibitor: A Sub-Analysis of the Natrium-HF Study

In a controlled acute volume overload setting, BNP and NT-proBNP provide comparable information, but their short-term dynamics lag behind clinical decongestion. Routine serial NP measurements at very short time intervals are unlikely to add incremental clinical value in the early phase of acute HF.

Authors

Institutions

Publication Details

Journal
ESC Heart Failure
Published
2026-03-14
DOI
https://doi.org/10.1093/eschf/xvag075
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Cardiac Biomarkers Response Under Angiotensin Receptor–Neprilysin Inhibitor: A Sub-Analysis of the Natrium-HF Study

Christopher Edwards, Gad Cotter, M. Sadoune, Alexis Nguyen et al.
ESC Heart Failure
Heart Failure Treatment and Management
article

Cardiac Biomarkers Response Under Angiotensin Receptor–Neprilysin Inhibitor: A Sub-Analysis of the Natrium-HF Study

Christopher Edwards, Gad Cotter, M. Sadoune, Alexis Nguyen, Elisabeth Masson, Aziz Daghmouri, Priyanka Morishetty, Camille Chenevier-Gobeaux, Romane LAFONTAINE, Jolie Bruno, B A Davison, Alexandre Mebazaa, Christos Varounis, Feriel Azibani, Benjamin Deniau, Koji Takagi
article en

Abstract

In a controlled acute volume overload setting, BNP and NT-proBNP provide comparable information, but their short-term dynamics lag behind clinical decongestion. Routine serial NP measurements at very short time intervals are unlikely to add incremental clinical value in the early phase of acute HF.

ESC Heart Failure
University of Bern (CH), Inserm (FR), Université Paris Cité (FR), University Hospital of Bern (CH), Abbott (United Kingdom) (GB), Abbott (United States) (US), Sorbonne Paris Cité (FR), Hôpital Cochin (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre Hospitalier Intercommunal André Grégoire Montreuil (FR), Hôpital Lariboisière (FR), Paris Cardiovascular Research Center (FR), Momentum Research (US)
Openalex Percentile: Top 29%
Heart Failure Treatment and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.