Changes in ultraviolet a radiation-induced thymidine dimers and erythema after oral nicotinamide or polypodium leucotomos extract in healthy volunteers: a randomized intraindividual trial

UVA-induced erythema was significantly reduced by PL and NAM, but neither had measurable effects on TT-dimer induction. Further research should investigate the relation between these findings and the chemopreventive effect of NAM and PL on skin cancer.

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Publication Details

Journal
Photochemical & Photobiological Sciences
Published
2026-03-16
DOI
https://doi.org/10.1007/s43630-026-00884-2
Primary Topic
Skin Protection and Aging
Type
article
Field-Weighted Citation Impact
0.00
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article

Changes in ultraviolet a radiation-induced thymidine dimers and erythema after oral nicotinamide or polypodium leucotomos extract in healthy volunteers: a randomized intraindividual trial

Celina Pihl, Thierry Douki, C. M. Lerche, T. Gregersen et al.
Photochemical & Photobiological Sciences
Skin Protection and Aging
article

Changes in ultraviolet a radiation-induced thymidine dimers and erythema after oral nicotinamide or polypodium leucotomos extract in healthy volunteers: a randomized intraindividual trial

Celina Pihl, Thierry Douki, C. M. Lerche, T. Gregersen, M. Haedersdal, P. A. Philipsen, S. R. Wiegell, Aheen Faisal, J. R. Granborg, P. Bjerring
article en

Abstract

UVA-induced erythema was significantly reduced by PL and NAM, but neither had measurable effects on TT-dimer induction. Further research should investigate the relation between these findings and the chemopreventive effect of NAM and PL on skin cancer.

Photochemical & Photobiological Sciences
Institut polytechnique de Grenoble (FR), University of Copenhagen (DK), Centre National de la Recherche Scientifique (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Aalborg University Hospital (DK), Bispebjerg Hospital (DK), Copenhagen University Hospital (DK), CEA Grenoble (FR), Aalborg University (DK), Université Grenoble Alpes (FR)
Good health and well-being
Openalex Percentile: Top 19%
Skin Protection and Aging
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