Advancing systems-based hematology

In this issue of Blood Advances, Godby et al 1 report findings from a qualitative study defining the principles, competencies, challenges, and future of systems-based hematology (SBH).This article is of relevance to all journal readers, whether they practice SBH or not, because it suggests that SBH could push the whole discipline of hematology forward.In 2015, Wallace et al introduced the concept of the systems-based hematologist, defined not just by what they treat, but by how they integrate hematology expertise across the entire health care system. 2 In 2020, May et al proposed a framework to categorize SBH work, citing examples such as diagnostic stewardship of hematologic disorders (heparin-induced thrombocytopenia); evidence-based use of hematologic therapies (blood products and anticoagulation); and innovations to improve access to hematologic expertise (electronic consultation and care pathways). 3 SBH adds value to health care systems through improved patient outcomes and cost savings. 4,5Yet this value is often overlooked, impeding investment in SBH positions.Lack of clear training and career development pathways further constrains growth. 6 The authors sought to define and formalize SBH to support education and practice.They conducted semistructured interviews with 8 experienced SBH providers, exploring career paths and essential skills.The authors performed a systematic thematic analysis, using a large language model (Google Gemini Pro 2.5).The following 5 foundational themes emerged (see figure):

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Publication Details

Journal
Blood Advances
Published
2026-03-16
DOI
https://doi.org/10.1182/bloodadvances.2025019149
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
Field-Weighted Citation Impact
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article

Advancing systems-based hematology

Menaka Pai, Shannon M. Bates
Blood Advances
Clinical Laboratory Practices and Quality Control
article

Advancing systems-based hematology

Menaka Pai, Shannon M. Bates
article en

Abstract

In this issue of Blood Advances, Godby et al 1 report findings from a qualitative study defining the principles, competencies, challenges, and future of systems-based hematology (SBH).This article is of relevance to all journal readers, whether they practice SBH or not, because it suggests that SBH could push the whole discipline of hematology forward.In 2015, Wallace et al introduced the concept of the systems-based hematologist, defined not just by what they treat, but by how they integrate hematology expertise across the entire health care system. 2 In 2020, May et al proposed a framework to categorize SBH work, citing examples such as diagnostic stewardship of hematologic disorders (heparin-induced thrombocytopenia); evidence-based use of hematologic therapies (blood products and anticoagulation); and innovations to improve access to hematologic expertise (electronic consultation and care pathways). 3 SBH adds value to health care systems through improved patient outcomes and cost savings. 4,5Yet this value is often overlooked, impeding investment in SBH positions.Lack of clear training and career development pathways further constrains growth. 6 The authors sought to define and formalize SBH to support education and practice.They conducted semistructured interviews with 8 experienced SBH providers, exploring career paths and essential skills.The authors performed a systematic thematic analysis, using a large language model (Google Gemini Pro 2.5).The following 5 foundational themes emerged (see figure):

Blood AdvancesVol. 10(6)
McMaster University (CA)
Openalex Percentile: Top 19%
Clinical Laboratory Practices and Quality Control
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