Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease Using <scp>PET</scp> and Plasma Biomarkers
Temporal modeling of plasma biomarkers provides comparable information to PET-based models, particularly for tau onset age, and can serve as a widely accessible tool for clinical assessment of biological disease severity. ANN NEUROL 2026.
Authors
- Ilya M. Nasrallah (ORCID: https://orcid.org/0000-0003-2346-7562)
- E. Q. Lee
- Alice Chen‐Plotkin (ORCID: https://orcid.org/0000-0002-3387-2038)
- Katheryn AQ Cousins
- Emily McGrew
- John A. Detre
- Paul A. Yushkevich
- Dawn Mechanic‐Hamilton
- Magdalena Korecka
- Leslie M. Shaw
- Christopher A. Brown
- Sandhitsu R. Das
- Corey T. McMillan
- David A. Wolk
- for the Alzheimer's Disease Neuroimaging Initiative
Institutions
- Alzheimer’s Disease Neuroimaging Initiative (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1002/ana.78194
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00