Prophylactic HPV Vaccination in Gynaecological Practice: Recommendations, Practices, and Challenges Reported in the ESGO-PERCH HPV Survey

The survey shows that HPV vaccination is often recommended beyond evidence-supported indications. Randomized trials have not demonstrated a reduction in CIN2+ recurrence with adjuvant vaccination, and no evidence supports vaccination in women with invasive gynaecological cancers. These findings reveal a gap between clinical practice and available evidence, highlighting the need for clearer, evidence-based guidance.

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Publication Details

Journal
Vaccines
Published
2026-03-16
DOI
https://doi.org/10.3390/vaccines14030269
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Prophylactic HPV Vaccination in Gynaecological Practice: Recommendations, Practices, and Challenges Reported in the ESGO-PERCH HPV Survey

Esra Bilir, Zoia Razumova, Houssein El Hajj, Andrej Cokan et al.
Vaccines
Cervical Cancer and HPV Research
article

Prophylactic HPV Vaccination in Gynaecological Practice: Recommendations, Practices, and Challenges Reported in the ESGO-PERCH HPV Survey

Esra Bilir, Zoia Razumova, Houssein El Hajj, Andrej Cokan, Tibor A. Zwimpfer, Sophie Denoël, Nina Dhollander, Murat Gultekin, Nicolò Bizzarri, Khayal Gasimli, Maria Kyrgiou, Joanna Kacperczyk-Bartnik, Marc Arbyn
article en

Abstract

The survey shows that HPV vaccination is often recommended beyond evidence-supported indications. Randomized trials have not demonstrated a reduction in CIN2+ recurrence with adjuvant vaccination, and no evidence supports vaccination in women with invasive gynaecological cancers. These findings reveal a gap between clinical practice and available evidence, highlighting the need for clearer, evidence-based guidance.

VaccinesVol. 14(3)
Goethe University Frankfurt (DE), United Nations (US), Koç University (TR), Imperial College Healthcare NHS Trust (GB), University of Basel (CH), Medical University of Warsaw (PL), Peter MacCallum Cancer Centre (AU), Institut Gustave Roussy (FR), University Hospital of Basel (CH), Agostino Gemelli University Polyclinic (IT), Karolinska Institutet (SE), Ghent University (BE), University of Maribor (SI), Nephrologisches Zentrum Goettingen (DE), National Institute of Oncology (HU), University Clinical Centre Maribor (SI), Hospital zum Heiligen Geist (DE), Sciensano (Belgium) (BE), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), Imperial College London (GB), Hacettepe University (TR)
Openalex Percentile: Top 22%
Cervical Cancer and HPV Research
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