Evaluation of the performance of the reference equations for single-breath diffusing capacity of the lung for carbon monoxide (DLCOsb) in Latin American populations at different altitudes: A multicentre study

Although with wide limits of agreement for all models, Vázquez-García's equation shows the best performance in the interpretation of DLCOsb in Latin American populations residing at any altitude. Even with adjustments for altitude and Hb, the GLI model underestimates the predicted values of DLCOsb and could require an adjustment factor or inclusion of the altitude variable in the model's new version.

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Publication Details

Journal
Pulmonology
Published
2026-03-16
DOI
https://doi.org/10.1080/25310429.2026.2638013
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

Evaluation of the performance of the reference equations for single-breath diffusing capacity of the lung for carbon monoxide (DLCOsb) in Latin American populations at different altitudes: A multicentre study

Carlos Aguirre-Franco, César Marcelo Delgado Viteri, Iván Chérrez-Ojeda, Ireri Isadora Thirión-Romero et al.
Pulmonology
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Evaluation of the performance of the reference equations for single-breath diffusing capacity of the lung for carbon monoxide (DLCOsb) in Latin American populations at different altitudes: A multicentre study

Carlos Aguirre-Franco, César Marcelo Delgado Viteri, Iván Chérrez-Ojeda, Ireri Isadora Thirión-Romero, Lorena Noriega, Luis is Torre-Bouscoulet, Emily Rincón-Álvarez, Natallie Jurado, Laura Gochicoa-Rangel, Guillermo Adolfo Arbo Oze de Morvil, Luis Giraldo-Cadavid, Sandra González Toledo
article en

Abstract

Although with wide limits of agreement for all models, Vázquez-García's equation shows the best performance in the interpretation of DLCOsb in Latin American populations residing at any altitude. Even with adjustments for altitude and Hb, the GLI model underestimates the predicted values of DLCOsb and could require an adjustment factor or inclusion of the altitude variable in the model's new version.

PulmonologyVol. 32(1)
Universidad de La Sabana (CO), Universidad Espíritu Santo (EC), Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES), Fundación Neumológica Colombiana (CO), Institute of Economic and Social Development (AR), Centro Médico ABC (MX), Hospital de Especialidades (MX)
Openalex Percentile: Top 21%
Chronic Obstructive Pulmonary Disease (COPD) Research
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