Infliximab-induced lupus with recurrent pericarditis: longitudinal CMR assessment of inflammatory resolution

Recurrent pericarditis is an uncommon extraintestinal manifestation of inflammatory bowel disease and may arise from biologic-induced autoimmunity. Anti–tumor necrosis factor (TNF) agents such as infliximab can trigger drug-induced lupus, with pericardial involvement representing a rare presentation. Cardiac magnetic resonance (CMR) enables precise evaluation of pericardial inflammation, guiding treatment strategies and supporting safe immunomodulatory tapering.