Total Synthesis of Polyacetylene‐Based Natural Products Facilitated by Cadiot–Chodkiewicz Coupling Reaction: A Review
Copper‐mediated carbon–carbon bond formation reactions are significant transformations in organic synthesis. In this context, Cadiot–Chodkiewicz cross‐coupling reaction has played a pivotal role in the designing of natural products, offering an efficient and powerful way to build intricate polyacetylenes. This account provides recent applications of Cadiot–Chodkiewicz coupling reaction toward the total synthesis of polyacetylene‐based natural products.
Authors
- Samreen Gul Khan
- Sajid Hussain (ORCID: https://orcid.org/0000-0002-3848-0981)
- Muhammad Naveed Anjum (ORCID: https://orcid.org/0000-0001-5622-8600)
- Usman Nazeer (ORCID: https://orcid.org/0009-0004-2598-7224)
- Muhammad Nadeem Abbas (ORCID: https://orcid.org/0000-0002-6314-0110)
- Asim Mansha
- Aijaz Rasool Chaudhry
- Samna Sohail
- Ahmad Irfan
- Ameer Fawad Zahoor
Institutions
- Government College University, Faisalabad (PK)
- Forman Christian College (PK)
- University of Bisha (SA)
- King Khalid University (SA)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1002/ejoc.202500704
- Primary Topic
- Plant chemical constituents analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00