Comparative Effectiveness of Antihypertensive Medications in Children With Chronic Kidney Disease
In this comparative-effectiveness study, RAASi was associated with lower risk of CKD progression and better blood pressure control compared to CCB. Findings support first-line use of RAASi for antihypertensive treatment in pediatric CKD.
Authors
- Chryso Katsoufis (ORCID: https://orcid.org/0000-0002-8872-1165)
- Michael D. Kappelman (ORCID: https://orcid.org/0000-0002-0469-6856)
- Benjamin L. Laskin (ORCID: https://orcid.org/0000-0002-9994-8509)
- B. Dixon
- Harold P. Lehmann (ORCID: https://orcid.org/0000-0002-7698-219X)
- Rebecca L. Ruebner
- Mark Mitsnefes (ORCID: https://orcid.org/0000-0002-9904-0250)
- Kimberley Dickinson (ORCID: https://orcid.org/0000-0001-9523-056X)
- Hanieh Razzaghi (ORCID: https://orcid.org/0000-0001-5001-1590)
- Keith A. Marsolo (ORCID: https://orcid.org/0000-0002-4416-1549)
- Eneida A. Mendonça (ORCID: https://orcid.org/0000-0003-4297-9221)
- Priya S. Verghese (ORCID: https://orcid.org/0000-0002-8836-0881)
- Hiren P. Patel (ORCID: https://orcid.org/0000-0003-4968-0943)
- David A. Hanauer (ORCID: https://orcid.org/0000-0001-6931-3791)
- Lyndsay A. Harshman (ORCID: https://orcid.org/0000-0003-4952-8132)
- Michelle Denburg (ORCID: https://orcid.org/0000-0002-0704-3607)
- Alicia M. Neu (ORCID: https://orcid.org/0000-0002-5638-4168)
- Caroline Gluck (ORCID: https://orcid.org/0000-0003-1880-2506)
- Keith Morse (ORCID: https://orcid.org/0000-0002-8307-1642)
- Amy C. Wilson (ORCID: https://orcid.org/0000-0001-6831-5875)
- Mary Beth Leonard (ORCID: https://orcid.org/0000-0002-8972-6582)
- Aneta Jovanovska
- Larry T. Patterson
- Bradley Taylor (ORCID: https://orcid.org/0000-0002-6414-4172)
- Zubin J. Modi (ORCID: https://orcid.org/0000-0003-4410-2853)
- Yungui Huang (ORCID: https://orcid.org/0000-0003-3265-9902)
- Daksha Ranade
- Dominick J. Lemas (ORCID: https://orcid.org/0000-0001-5105-2458)
- Dorey A. Glenn (ORCID: https://orcid.org/0000-0003-2796-3037)
- Mitchell Maltenfort (ORCID: https://orcid.org/0000-0002-0141-1720)
- Donna Claes (ORCID: https://orcid.org/0000-0002-1041-1378)
- Amy Goodwin Davies (ORCID: https://orcid.org/0000-0002-2942-4654)
- Marc B. Rosenman
- Mark Levondosky
- Rebecca Levondosky
- Elana Dicocco
- Cynthia G. Pan
- Sara Deakyne Davies
- Kaleigh Wieand
- Jarcy Zee
- Christopher B. Forrest
- L. Charles Bailey
- Levon Utidjian
- Lu Li
- Cynthia Wong
- A. Samuel Boss
- K.T. Sandra Ilunga
- Elizabeth Chrischilles
- Vikas Dharnidharka
- H. Timothy Bunnell
- Yong Chen
- Morgan Botdorf
- Joseph T. Flynn
Institutions
- Northwestern University (US)
- University of North Carolina at Chapel Hill (US)
- Children's Hospital of Wisconsin (US)
- Cincinnati Children's Hospital Medical Center (US)
- Lurie Children's Hospital (US)
- Seattle Children's Hospital (US)
- Nationwide Children's Hospital (US)
- UF Health Shands Hospital (US)
- Children's Hospital of Philadelphia (US)
- Johns Hopkins University (US)
- University of Washington (US)
- Associated Press (US)
- Riley Hospital for Children (US)
- Children's Hospital Colorado (US)
- University of Iowa Stead Family Children’s Hospital (US)
- Stanford Health Care (US)
- Children's Health Council (US)
- Nemours Children's Health System (US)
- University of Miami Hospital (US)
- Johns Hopkins Children's Center (US)
- C. S. Mott Children's Hospital (US)
- The Ohio State University (US)
- Indiana University – Purdue University Indianapolis (US)
- University of Cincinnati (US)
- University of Pennsylvania (US)
- University of Colorado Denver (US)
- Stanford University (US)
Publication Details
- Journal
- JAMA Pediatrics
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1001/jamapediatrics.2026.0207
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00