An inflammatory biomarker panel for prediabetes classification using interpretable machine learning
Our findings introduce a novel panel of inflammatory biomarkers that show promise in the identification of prediabetes independently of traditional glucose-based measures. By highlighting inflammation as an early indicator of metabolic dysfunction, this approach may enhance precision in the detection of prediabetes. Longitudinal studies with larger and more diverse populations are essential to clinically validate these biomarkers and confirm their value in improving the early diagnosis and management of metabolic health.
Authors
- Maher Maalouf (ORCID: https://orcid.org/0000-0003-0516-6870)
- Maram Tammam
- Asmaa Alsereidi
- Herbert F. Jelinek
- Muhammad Afzal
- Sana Kurungadan
Institutions
- Khalifa University of Science and Technology (AE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1371/journal.pone.0341195
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00