Hydralazine Use and Risk of Vasculitis

In this cohort study of adults who were newly prescribed hydralazine, vasculitis associated with hydralazine was rare, despite multiple reported cases. Use of hydralazine is unlikely to be associated with a clinically meaningful increased risk of vasculitis.

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Publication Details

Journal
JAMA Network Open
Published
2026-03-16
DOI
https://doi.org/10.1001/jamanetworkopen.2026.1943
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Hydralazine Use and Risk of Vasculitis

Manish M. Sood, Mark Canney, Shan Dhaliwal, Gregory L. Hundemer et al.
JAMA Network Open
Vasculitis and related conditions
article

Hydralazine Use and Risk of Vasculitis

Manish M. Sood, Mark Canney, Shan Dhaliwal, Gregory L. Hundemer, Ayub Akbari, Deena Fremont, David Massicotte-Azarniouch, Vimal K. Derebail
article en

Abstract

In this cohort study of adults who were newly prescribed hydralazine, vasculitis associated with hydralazine was rare, despite multiple reported cases. Use of hydralazine is unlikely to be associated with a clinically meaningful increased risk of vasculitis.

JAMA Network OpenVol. 9(3)
University of North Carolina at Chapel Hill (US), University of Ottawa (CA), Ottawa Hospital (CA), Ottawa Hospital Research Institute (CA)
Good health and well-being
Openalex Percentile: Top 21%
Vasculitis and related conditions
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