Simultaneous Quantification of Twelve Endogenous HPA Axis Compounds by Protein Precipitation and HILIC‐UPLC–MS/MS in a Mouse Model of Insomnia
The proposed method exhibited excellent performance in terms of linearity, precision, accuracy, stability, and matrix effects, demonstrating superior practicality and reliability for the analysis of complex biological samples.
Authors
- Dan Su (ORCID: https://orcid.org/0000-0002-4660-2168)
- Ming Yang (ORCID: https://orcid.org/0000-0002-0020-8683)
- Wei Long (ORCID: https://orcid.org/0000-0002-5365-9111)
- Yuyu Liu (ORCID: https://orcid.org/0000-0002-4814-8616)
- Zhifu Ai
- Yonggui Song
- Yuhui Ping
- Wei Huang
- Tao luo
- Genhua Zhu
- Jiale Li
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Nanchang University (CN)
- Changzhou No.2 People's Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1002/rcm.70063
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00