Unlocking the predictive value of post-neoadjuvant immune biomarkers in breast cancer: neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII)
Post-treatment NLR and SII may reflect chemotherapy-induced immune changes and are associated with pathological complete response, but their additional predictive value is uncertain, and no prognostic impact was observed.
Authors
- Caridad Marín Hernández (ORCID: https://orcid.org/0000-0002-1708-9166)
- Noel Blaya Boluda
- C Lema
- Elisa García Garre
- Pedro Marín Rodríguez
- E. García-Martínez
- Francisco Ayala de la Peña
- Pilar Sánchez Henarejos
- Pilar de la Morena Barrio
- E. García-Torralba
- Antonio Piñero Madrona
- Andrea Gottlob Pérez
- María Esperanza Guirao García
- Miguel Ángel Moya Hernández
Institutions
- Hospital General Universitario Morales Meseguer (ES)
- Instituto Murciano de Investigación Biosanitaria (ES)
- Hospital Universitario Virgen de la Arrixaca (ES)
- Universidad de Murcia (ES)
Publication Details
- Journal
- Breast Cancer Research and Treatment
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1007/s10549-026-07928-2
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00