Exploring the Relationship Between <scp> <i>MDM</i> 4 </scp> Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

The MDM4 rs1380576 C>G polymorphism, particularly the CC genotype, is associated with increased BC risk in Bangladeshi women, whereas rs4245739 A>C shows no association. These findings suggest rs1380576 may serve as a potential genetic marker for BC susceptibility in this population.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2026-03-15
DOI
https://doi.org/10.1002/jcla.70199
Primary Topic
Cancer-related Molecular Pathways
Type
article
Field-Weighted Citation Impact
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article

Exploring the Relationship Between MDM 4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

Md. Aminul Haque, Md Shaki Mostaid, Md. Shafiqul Islam, Rabiul Islam et al.
Journal of Clinical Laboratory Analysis
Cancer-related Molecular Pathways
article

Exploring the Relationship Between MDM 4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

Md. Aminul Haque, Md Shaki Mostaid, Md. Shafiqul Islam, Rabiul Islam, Sharif Ahamed, J. M. Aousiful Islam, M. Mahboob Hossain, Md Sadbean Hossain
article en

Abstract

The MDM4 rs1380576 C>G polymorphism, particularly the CC genotype, is associated with increased BC risk in Bangladeshi women, whereas rs4245739 A>C shows no association. These findings suggest rs1380576 may serve as a potential genetic marker for BC susceptibility in this population.

Journal of Clinical Laboratory Analysis
Betsi Cadwaladr University Health Board (GB), North South University (BD), IBAIS University (BD), BRAC University (BD)
Good health and well-being
Openalex Percentile: Top 21%
Cancer-related Molecular Pathways
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