Facilitators and Barriers for Implementing Diagnostic Sequencing Technology for Pediatric Oncology in Low‐ and Middle‐Income Countries

Participants communicated that the lack of diagnostic classification for pediatric cancer in LMICs is a common key limitation to current cancer care. They described considerable motivating strengths to leverage toward this goal of developing sequencing-based diagnostic testing capacity. Resource availability, continuity, and sustainability are current barriers that must be addressed. Our data highlight the urgent need for creative global implementation partnerships as many centers in LMICs are poised to advance novel diagnostic solutions.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2026-03-15
DOI
https://doi.org/10.1002/1545-5017.70207
Primary Topic
Genomics and Rare Diseases
Type
article
Field-Weighted Citation Impact
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article

Facilitators and Barriers for Implementing Diagnostic Sequencing Technology for Pediatric Oncology in Low‐ and Middle‐Income Countries

Kenneth Busby, Gevorg Tamamyan, Jamie Zeal, Rui Manuel Reis et al.
Pediatric Blood & Cancer
Genomics and Rare Diseases
article

Facilitators and Barriers for Implementing Diagnostic Sequencing Technology for Pediatric Oncology in Low‐ and Middle‐Income Countries

Kenneth Busby, Gevorg Tamamyan, Jamie Zeal, Rui Manuel Reis, Adriana Navas, Stuart Rennie, Javeria Aijaz, Patricia Alcasabas, Federico Guillermo Antillon‐Klussmann, Samantha Rubio, Vaskar Saha, Dylan Graetz, Megan C. Roberts, Eva Cutiongdo‐de la Paz, Nathaniel Webb, Nickhill Bhakta, Thomas B. Alexander
article en

Abstract

Participants communicated that the lack of diagnostic classification for pediatric cancer in LMICs is a common key limitation to current cancer care. They described considerable motivating strengths to leverage toward this goal of developing sequencing-based diagnostic testing capacity. Resource availability, continuity, and sustainability are current barriers that must be addressed. Our data highlight the urgent need for creative global implementation partnerships as many centers in LMICs are poised to advance novel diagnostic solutions.

Pediatric Blood & Cancer
University of North Carolina at Chapel Hill (US), St. Jude Children's Research Hospital (US), Emory University (US), Indus Hospital (PK), Philippine General Hospital (PH), Tata Medical Center (IN), Hospital de Câncer de Barretos (BR), Center of Medical Genetics and Primary Health Care (AM), Universidad Francisco Marroquín (GT), University of the Philippines Manila (PH)
Partnerships for the goals
Openalex Percentile: Top 21%
Genomics and Rare Diseases
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