Evaluation of new 5-benzylidenethiazolidin-2,4-dione derivatives linked to nitric oxide donor oxime moiety as VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative assessment and <i>in silico</i> studies

The present work flags the approach for advanced expansion of powerful nitric oxide donor offshoots as VEGFR-2 inhibitors.

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Publication Details

Journal
Future Medicinal Chemistry
Published
2026-03-16
DOI
https://doi.org/10.1080/17568919.2026.2642678
Primary Topic
Angiogenesis and VEGF in Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of new 5-benzylidenethiazolidin-2,4-dione derivatives linked to nitric oxide donor oxime moiety as VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative assessment and in silico studies

Fatma Magdy, Wael A. A. Fadaly, Taha H. Zidan, Abeer M. Abd El-Hameed et al.
Future Medicinal Chemistry
Angiogenesis and VEGF in Cancer
article

Evaluation of new 5-benzylidenethiazolidin-2,4-dione derivatives linked to nitric oxide donor oxime moiety as VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative assessment and in silico studies

Fatma Magdy, Wael A. A. Fadaly, Taha H. Zidan, Abeer M. Abd El-Hameed, Naglaa M. Ahmed, May El-Manawaty
article en

Abstract

The present work flags the approach for advanced expansion of powerful nitric oxide donor offshoots as VEGFR-2 inhibitors.

Future Medicinal Chemistry
Beni-Suef University (EG), Taibah University (SA), National Research Centre (EG), Helwan University (EG)
Clean water and sanitation
Openalex Percentile: Top 20%
Angiogenesis and VEGF in Cancer
DOISourceOpenAlex
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