LAMB1 regulates COL3A1 and RAC1 expression during subchorionic hemorrhage progression
LAMB1 promotes inflammation and coagulation dysfunction in SCH by regulating COL3A1 and RAC1 expression. Targeting LAMB1 may offer a novel strategy for early diagnosis and therapeutic intervention in SCH to improve pregnancy outcomes.
Authors
- Xiaoyan Wu (ORCID: https://orcid.org/0000-0002-8302-036X)
- Guixue Guan
- Conghui Han (ORCID: https://orcid.org/0000-0003-3008-675X)
- Qian Sun
- Jinjin Xu
- Shun Liu (ORCID: https://orcid.org/0009-0005-1859-4390)
- Li Zhang (ORCID: https://orcid.org/0000-0002-3617-2627)
- Fan Shi (ORCID: https://orcid.org/0000-0002-8033-4670)
- Yuhuan Wang (ORCID: https://orcid.org/0000-0002-7487-1402)
- Zuobin Zhu
- Wen Feng
- Xiaopei Li
- Yuan Gao
- Xiaozuo Zhang
- Jing Ji
- Wen Yang
- Hengmin Bi
Institutions
- Jiangsu Normal University (CN)
- China Pharmaceutical University (CN)
- Xuzhou Medical College (CN)
- The First People’s Hospital of Lianyungang (CN)
- Heilongjiang Provincial Hospital (CN)
- Xuzhou Central Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1186/s12915-026-02574-y
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00