Vitamin K antagonists and structural valve deterioration in bioprosthetic aortic valves

After bioprosthetic AVR, VKA exposure and porcine bioprostheses were independently associated with SVD. Antithrombotic strategies should consider the potential long-term adverse effects of VKA in the context of prosthesis material and patient characteristics. Prospective multicenter studies are needed to confirm these findings.

Authors

Serdar Bayrak
Şevket Uǧurlu
Onur Barış Dayanır (ORCID: https://orcid.org/0000-0003-1293-3898)
Tuğra Gençpınar (ORCID: https://orcid.org/0000-0003-4438-7991)
Ceren Sayarer
Fatih Emre Kılıç

Institutions

Dokuz Eylül University (TR)
Sivas State Hospital (TR)

Publication Details

Journal: Turkish Journal of Thoracic and Cardiovascular Surgery
Published: 2026-03-16
DOI: https://doi.org/10.4274/tjtcs.2026.28879
Primary Topic: Cardiac Valve Diseases and Treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

Vitamin K antagonists and structural valve deterioration in bioprosthetic aortic valves

Serdar Bayrak, Şevket Uǧurlu, Onur Barış Dayanır, Tuğra Gençpınar et al.

Mar 16, 2026

Turkish Journal of Thoracic and Cardiovascular Surgery

Cardiac Valve Diseases and Treatments

article

Vitamin K antagonists and structural valve deterioration in bioprosthetic aortic valves

Serdar Bayrak, Şevket Uǧurlu, Onur Barış Dayanır, Tuğra Gençpınar, Ceren Sayarer, Fatih Emre Kılıç

March 16, 2026article en

Abstract

After bioprosthetic AVR, VKA exposure and porcine bioprostheses were independently associated with SVD. Antithrombotic strategies should consider the potential long-term adverse effects of VKA in the context of prosthesis material and patient characteristics. Prospective multicenter studies are needed to confirm these findings.

Turkish Journal of Thoracic and Cardiovascular Surgery

Dokuz Eylül University (TR), Sivas State Hospital (TR)

Openalex Percentile: Top 29%

Cardiac Valve Diseases and Treatments

DOI Open Access PDF OpenAlex

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