Efficacy and Safety of Baclofen 40 mg/20 mL in an Intrathecal Infusion System

Switching to baclofen 40 mg/20 mL is safe and clinically equivalent to the conventional 10 mg/5 mL formulation when the daily dose is maintained unchanged. Dose reduction appears unsuitable in patients requiring high daily intrathecal baclofen doses.

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Publication Details

Journal
Life
Published
2026-03-14
DOI
https://doi.org/10.3390/life16030473
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Baclofen 40 mg/20 mL in an Intrathecal Infusion System

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Life
Botulinum Toxin and Related Neurological Disorders
article

Efficacy and Safety of Baclofen 40 mg/20 mL in an Intrathecal Infusion System

Maurizio Ranieri, Serena Gervasi, Marisa Megna, Riccardo Marvulli, Lucrezia dell’Olio, Giuseppa Lagioia, Serena Caforio Montesardo
article en

Abstract

Switching to baclofen 40 mg/20 mL is safe and clinically equivalent to the conventional 10 mg/5 mL formulation when the daily dose is maintained unchanged. Dose reduction appears unsuitable in patients requiring high daily intrathecal baclofen doses.

LifeVol. 16(3)
University of Bari Aldo Moro (IT)
Good health and well-being
Openalex Percentile: Top 28%
Botulinum Toxin and Related Neurological Disorders
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