Genomic Landscape of Myoepithelial Carcinoma Tumors
Despite sharing a chromosomal translocation partner (the EWSR1 gene) with sarcomas, MECA are most related to other salivary carcinomas. Further exploration of IGF1R as a therapeutic target in MECA is warranted. We also make available the 27 patients' next generation DNA exome and RNA sequencing through the EGA Repository.
Authors
- Charles Keller (ORCID: https://orcid.org/0000-0003-2505-7487)
- Lindsay H. Ryan (ORCID: https://orcid.org/0000-0001-8498-2539)
- Ryan D. Roberts (ORCID: https://orcid.org/0000-0001-5028-744X)
- Paul H. Huang (ORCID: https://orcid.org/0000-0003-3972-5087)
- Sonja Chen (ORCID: https://orcid.org/0000-0001-6174-8723)
- Yuen B. Tam (ORCID: https://orcid.org/0000-0002-1319-5148)
- Robin L. Jones (ORCID: https://orcid.org/0000-0003-4173-3844)
- Amy C. Gross (ORCID: https://orcid.org/0000-0002-0123-5085)
- Ganapati Srinivasa
- Morgan Darrow
- Melissa Sammons
- Hollis Wright
- Prof Khin Thway
- Melvin Lathara
- Mayukha Kashyap
- JiHyeon Byun
- Anandhi Mandi
- Geoffrey B. Alintoff
Institutions
- Nationwide Children's Hospital (US)
- Institute of Cancer Research (GB)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- ZRT Laboratory (US)
- Royal Marsden Hospital (GB)
- Children's Cancer Therapy Development Institute (US)
- University of California, Davis (US)
Publication Details
- Journal
- Oral Diseases
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1111/odi.70293
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00