Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease

Weekly 80 mg adalimumab appears to be an effective and well-tolerated intensification strategy in pediatric CD patients with pharmacokinetic loss of response. Further prospective studies are needed to confirm these findings and guide optimal use.

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Publication Details

Journal
Journal of Pediatric Gastroenterology and Nutrition
Published
2026-03-15
DOI
https://doi.org/10.1002/jpn3.70397
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
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article

Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease

Esther Orlanski‐Meyer, Yael Weintraub, R. Shamir, Raouf Nassar et al.
Journal of Pediatric Gastroenterology and Nutrition
Inflammatory Bowel Disease
article

Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease

Esther Orlanski‐Meyer, Yael Weintraub, R. Shamir, Raouf Nassar, Eyal Cohen‐Sela, Firas Rinawi, Manar Matar, Dror S. Shouval, Anat Yerushalmy‐Feler, Ramit Magen‐Rimon
article en

Abstract

Weekly 80 mg adalimumab appears to be an effective and well-tolerated intensification strategy in pediatric CD patients with pharmacokinetic loss of response. Further prospective studies are needed to confirm these findings and guide optimal use.

Journal of Pediatric Gastroenterology and Nutrition
Tel Aviv University (IL), Technion – Israel Institute of Technology (IL), Emek Medical Center (IL), Soroka Medical Center (IL), Rambam Health Care Campus (IL), Shaare Zedek Medical Center (IL), Schneider Children's Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 21%
Inflammatory Bowel Disease
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