Poststroke Depression and Anxiety: A Comprehensive Topical Review

Mental health issues after stroke are common and have a significant negative impact on functional outcomes, quality of life, and longevity. Despite their prevalence and impact, these conditions remain underrecognized and undertreated. This topical review synthesizes current evidence on the epidemiology, mechanisms, assessments, and treatments related to poststroke depression and anxiety, the most common neuropsychological sequelae after stroke, and identifies gaps and future directions.