The Effect of Adjunctive Systemic Antibiotics on the Outcomes of Non‐Surgical Periodontal Therapy: A Retrospective Cohort Study

Adjunctive systemic antibiotics, particularly the amoxicillin + metronidazole combination, significantly enhance clinical outcomes in non-surgical periodontitis treatment compared to SRP alone, with the greatest benefits seen in severe disease.

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Publication Details

Journal
Journal Of Clinical Periodontology
Published
2026-03-16
DOI
https://doi.org/10.1111/jcpe.70117
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Effect of Adjunctive Systemic Antibiotics on the Outcomes of Non‐Surgical Periodontal Therapy: A Retrospective Cohort Study

Georgios S. Chatzopoulos, Larry F. Wolff
Journal Of Clinical Periodontology
Oral microbiology and periodontitis research
article

The Effect of Adjunctive Systemic Antibiotics on the Outcomes of Non‐Surgical Periodontal Therapy: A Retrospective Cohort Study

Georgios S. Chatzopoulos, Larry F. Wolff
article en

Abstract

Adjunctive systemic antibiotics, particularly the amoxicillin + metronidazole combination, significantly enhance clinical outcomes in non-surgical periodontitis treatment compared to SRP alone, with the greatest benefits seen in severe disease.

Journal Of Clinical Periodontology
University of Minnesota (US), Aristotle University of Thessaloniki (GR)
Openalex Percentile: Top 22%
Oral microbiology and periodontitis research
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