Granulocyte and monocyte adsorption therapy in sepsis: a propensity score-matched analysis
In this multi-dataset analysis, patients treated with G1-DHP showed lower mortality and more favorable clinical outcomes in comparison to external controls. These exploratory findings provide preliminary insights into the potential role of G1-DHP as an immunomodulatory approach in sepsis and warrant further evaluation in prospective studies.
Authors
- Takuma Ishihara (ORCID: https://orcid.org/0000-0002-1979-8310)
- Osamu Nishida (ORCID: https://orcid.org/0000-0003-0140-283X)
- Kazuhiro Moriyama (ORCID: https://orcid.org/0000-0002-5598-6669)
- Ryo Hisamune (ORCID: https://orcid.org/0009-0009-3339-1902)
- Gaku Takahashi (ORCID: https://orcid.org/0000-0002-5947-6295)
- Tomoyuki Nakamura
- Kazuma Yamakawa
- Kent Doi
Institutions
- Fujita Health University (JP)
- Iwate Medical University (JP)
- Gifu University Hospital (JP)
- Iwate Prefectural University (JP)
- The University of Tokyo (JP)
- Osaka University of Pharmaceutical Sciences (JP)
Publication Details
- Journal
- Journal of Intensive Care
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1186/s40560-026-00872-9
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00