Risk Factors for Bleeding Following Combined Catheter Ablation and Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation and Low Baseline Bleeding Risk: An Exploratory Analysis

In this exploratory, hypothesis-generating analysis of NVAF patients with low HAS-BLED scores undergoing combined CA and LAAO, renal insufficiency, history of MI, and advanced age were associated with bleeding events. These findings suggest that conventional risk scores may not fully capture bleeding risk in this setting but require validation in larger, prospective multicenter cohorts before clinical application.

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Publication Details

Journal
Cureus
Published
2026-03-16
DOI
https://doi.org/10.7759/cureus.105313
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk Factors for Bleeding Following Combined Catheter Ablation and Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation and Low Baseline Bleeding Risk: An Exploratory Analysis

Hengli Lai, Z. Chen, Haoqing Ren
Cureus
Atrial Fibrillation Management and Outcomes
article

Risk Factors for Bleeding Following Combined Catheter Ablation and Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation and Low Baseline Bleeding Risk: An Exploratory Analysis

Hengli Lai, Z. Chen, Haoqing Ren
article en

Abstract

In this exploratory, hypothesis-generating analysis of NVAF patients with low HAS-BLED scores undergoing combined CA and LAAO, renal insufficiency, history of MI, and advanced age were associated with bleeding events. These findings suggest that conventional risk scores may not fully capture bleeding risk in this setting but require validation in larger, prospective multicenter cohorts before clinical application.

CureusVol. 18(3)
Nanchang University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial People's Hospital (CN)
Openalex Percentile: Top 30%
Atrial Fibrillation Management and Outcomes
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