Heat Acclimation Training Attenuates Oxidative Stress and Improves Mitochondrial Function to Protect the Heart from Exertional Heat Stroke in Mice

This work identifies transcriptional alterations and signaling pathways associated with EHS-induced myocardial injury, suggesting pivotal roles for mitochondrial dysfunction and oxidative stress. Additionally, this research provides a theoretical basis and potential intervention targets for the prevention and mitigation of heat stress-induced cardiovascular damage through HA training.