Association Between Maternal Infection During Pregnancy and the Risk of Childhood Acute Lymphoblastic Leukemia in Offspring: A Systematic Review and Meta‐Analysis
Maternal infections during pregnancy, particularly influenza, are associated with an increased risk of childhood ALL, and borderline associations were observed for EBV and respiratory infections. The observed risk from genitourinary infections may have come from confounding. These findings emphasize the clinical importance of influenza prevention and the timely management of prenatal infections.
Authors
- Weixia Yu (ORCID: https://orcid.org/0009-0003-4237-1862)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Minghong Liu (ORCID: https://orcid.org/0000-0002-5102-1915)
- Maggie Chen (ORCID: https://orcid.org/0000-0001-6573-4134)
- Jianzheng Cai
- Shiping Wang
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1002/1545-5017.70222
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00