Eligibility criteria in phase 3 randomized controlled trials in metastatic non–small cell lung cancer

The eligibility criteria in phase 3 RCTs in metastatic NSCLC continue to be strict. In some trials, judicious modifications of these criteria should be considered to improve the enrollment of clinically relevant populations of patients, especially older adults, individuals with an ECOG score of 2, and those with selected comorbidities.

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Publication Details

Journal
Cancer
Published
2026-03-15
DOI
https://doi.org/10.1002/cncr.70361
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Eligibility criteria in phase 3 randomized controlled trials in metastatic non–small cell lung cancer

Danuta Kłosowska, Jan Borysowski, Magdalena Knetki‐Wróblewska, M. Krzakowski et al.
Cancer
Lung Cancer Treatments and Mutations
article

Eligibility criteria in phase 3 randomized controlled trials in metastatic non–small cell lung cancer

Danuta Kłosowska, Jan Borysowski, Magdalena Knetki‐Wróblewska, M. Krzakowski, Marek Harhala
article en

Abstract

The eligibility criteria in phase 3 RCTs in metastatic NSCLC continue to be strict. In some trials, judicious modifications of these criteria should be considered to improve the enrollment of clinically relevant populations of patients, especially older adults, individuals with an ECOG score of 2, and those with selected comorbidities.

CancerVol. 132(6)
Medical University of Warsaw (PL), National Institute of Oncology (HU), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), Adam Mickiewicz University in Poznań (PL)
Good health and well-being
Openalex Percentile: Top 21%
Lung Cancer Treatments and Mutations
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