Regional Nasal Drug Deposition in Pediatric vs. Adult Models: In vitro Insights into User Technique and Breathing Patterns Sensitivity
This study demonstrates the potential for targeted drug delivery by enabling the identification of the optimal administration parameters to achieve desired outcomes, such as enhanced drug deposition in specific nasal regions.
Authors
- Theodore A. Schuman (ORCID: https://orcid.org/0000-0001-8325-5700)
- Anubhav Kaviratna
- Michael Hindle (ORCID: https://orcid.org/0000-0002-1025-1183)
- Bryan Newman (ORCID: https://orcid.org/0000-0002-8259-9277)
- Laleh Golshahi (ORCID: https://orcid.org/0000-0003-3450-7160)
- Ross Walenga (ORCID: https://orcid.org/0000-0003-3261-4245)
- Xiomara Owen
- Worth Longest
- Steven Chopski
- Mohammad Hejazi
- David J. Edwards
Institutions
- United States Food and Drug Administration (US)
- Center for Drug Evaluation and Research (US)
- Virginia Commonwealth University (US)
- Children's Hospital of Richmond at VCU (US)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1007/s11095-026-04066-8
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00