Left atrial sphericity and strain augment risk prediction in patients with embolic stroke of undetermined source

LA reservoir and conduit strain, and circularity have independent and incremental association with occurrence of recurrent-stroke and new-AF in ESUS patients. This may represent measurable non-invasive markers of atrial cardiomyopathy in a subset of ESUS patients, and enable risk-stratification, and targeted intervention. Future longitudinal studies are needed to confirm these findings.

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Publication Details

Journal
European Heart Journal - Cardiovascular Imaging
Published
2026-03-08
DOI
https://doi.org/10.1093/ehjci/jeag066
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Left atrial sphericity and strain augment risk prediction in patients with embolic stroke of undetermined source

Aaisha Ferkh, Faraz Ahmed Pathan, Andrew Duggins, Amy Clark et al.
European Heart Journal - Cardiovascular Imaging
Cardiovascular Function and Risk Factors
article

Left atrial sphericity and strain augment risk prediction in patients with embolic stroke of undetermined source

Aaisha Ferkh, Faraz Ahmed Pathan, Andrew Duggins, Amy Clark, Nina Marty Pangilinan, Sai Nagaratnam, Nalin Kataria, P. Brown, L. Stefani, Katty Duong, Liza Thomas
article en

Abstract

LA reservoir and conduit strain, and circularity have independent and incremental association with occurrence of recurrent-stroke and new-AF in ESUS patients. This may represent measurable non-invasive markers of atrial cardiomyopathy in a subset of ESUS patients, and enable risk-stratification, and targeted intervention. Future longitudinal studies are needed to confirm these findings.

European Heart Journal - Cardiovascular Imaging
The University of Sydney (AU), Nepean Hospital (AU), Westmead Hospital (AU), UNSW Sydney (AU), Westmead Institute (AU)
Openalex Percentile: Top 30%
Cardiovascular Function and Risk Factors
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Left atrial sphericity and strain augment risk prediction in patients with embolic stroke of undetermined source — Aaisha Ferkh, Faraz Ahmed Pathan, et al. · European Heart Journal - Cardiovascular Imaging (2026) | TGRS Research Map | TGRS