Delayed urticaria during treatment with anti‐ <scp>CGRP</scp> monoclonal antibodies in migraine

Anti-CGRP mAb-associated urticaria in this case series was delayed and likely non-immunoglobulin E (non-IgE)-mediated. Our experience supports that in selected patients with delayed urticaria, individualized management, including H1 antihistamine premedication, may allow continuation of effective migraine prophylaxis. Larger cohorts are needed to identify risk factors and to inform general management recommendations.

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Publication Details

Journal
Headache The Journal of Head and Face Pain
Published
2026-03-15
DOI
https://doi.org/10.1111/head.70082
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Delayed urticaria during treatment with anti‐ CGRP monoclonal antibodies in migraine

Lukas Heydrich, Athina Papadopoulou, Severin B. Vogt, Federico Burguet Villena et al.
Headache The Journal of Head and Face Pain
Migraine and Headache Studies
article

Delayed urticaria during treatment with anti‐ CGRP monoclonal antibodies in migraine

Lukas Heydrich, Athina Papadopoulou, Severin B. Vogt, Federico Burguet Villena, Karin Hartmann, Christoph T. Berger
article en

Abstract

Anti-CGRP mAb-associated urticaria in this case series was delayed and likely non-immunoglobulin E (non-IgE)-mediated. Our experience supports that in selected patients with delayed urticaria, individualized management, including H1 antihistamine premedication, may allow continuation of effective migraine prophylaxis. Larger cohorts are needed to identify risk factors and to inform general management recommendations.

Headache The Journal of Head and Face Pain
University of Basel (CH), Kunstmuseum Basel (CH), University Hospital of Bern (CH), University Hospital of Basel (CH), Department of Biomedicine Basel (CH)
Good health and well-being
Openalex Percentile: Top 30%
Migraine and Headache Studies
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