Impact of visceral adipose tissue and skeletal muscle on early and long-term biologic treatment failure in Crohn’s disease: A multicenter retrospective cohort study
Elevated VAT and reduced SM were associated with loss of response in CD biologics. The predictive model integrating body composition parameters demonstrated good performance.
Authors
- Quanrongzi Wang
- Chunhua Jiao (ORCID: https://orcid.org/0009-0003-3548-3591)
- Meijiao Lu (ORCID: https://orcid.org/0009-0006-4386-4994)
- Xiaojing Zhao
- Qiong Guo
- Jingjing Ma
- Jie Chen
- Hongjie Zhang
- Nana Tang
Institutions
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Northern Jiangsu People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1093/ibd/izag023
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00